Mar
7
Wed
Medicine Grand Rounds: Antisense controls neurodegeneration @ LKSC, Berg Hall
Mar 7 @ 8:00 am – 9:00 am
Medicine Grand Rounds: Antisense controls neurodegeneration @ LKSC, Berg Hall | Palo Alto | California | United States

Presenter: John Day, MD, PhD
Professor of Neurology, Genetic Pediatrics, and, by courtesy, Pathology
Stanford University

John Day, MD, PhD, works with the Neuromuscular Division, which organizes a comprehensive effort to combat and conquer diseases of the peripheral nerves and muscles, including the muscular dystrophies (myotonic, Duchenne, limb girdle, facioscapulohumeral, and congenital muscular dystrophies), motor neuron disorders (ALS and SMA), neuromuscular junction disease (MG, CMS), and peripheral neuropathies (CMT, CIDP). While keeping the patients and families foremost in mind, their research seeks to: define and understand genetic causes; clarify the molecular and cellular consequences of genetic change; determine the multisystemic features that are underappreciated but clinically significant consequence of these diseases; develop and improve methods for managing and treating each disease.

They have identified the genetic cause of several neuromuscular disorders, most notably myotonic dystrophy type 2, which they continue to study to advance understanding of all forms of myotonic dystrophy. They have also contributed to genetic understanding of Duchenne muscular dystrophy, and other muscle and ataxic disorders. They are continuing to investigate the epigenetic and molecular consequences of these diseases through investigation of patient-derived specimens.

They have focused on defining the central nervous system features of neuromuscular disorders, which severely impact patients and families but have been incompletely investigated, explained or managed. Detailed neuropsychological and brain MRI studies are helping to define the developmental and progressive CNS aspects of these conditions, for which they then seek molecular and cellular explanations through cell-based studies of patient-derived specimens.

To assure their research is translatable to clinical practice, they are simultaneously involved in collaborative clinical research on novel treatments for neuromuscular disease, including antisense oligonucleotides and pharmacologic manipulation of muscle function, viral gene therapies and cell-based treatments.

In summary, they work with patients to define neuromuscular disorders more rigorously and understand them more thoroughly, so novel treatments will successfully combat these devastating disorders.

Aug
27
Thu
Supporting Children in the Time of COVID-19 A School Based Approach to Health & Wellbeing @ Online Event
Aug 27 @ 8:00 am – 10:00 am
Supporting Children in the Time of COVID-19  A School Based Approach to Health & Wellbeing @ Online Event

Register here

In the wake of the COVID-19 pandemic, several support structures for children and their families have been disrupted. Underserved communities who were already disadvantaged prior to the pandemic now face further setbacks with regards to accessing digital resources, mental health services, food and housing support, and remote learning. On the frontlines of this battle are our educators who are grappling with the complexities of how to support their students during these uncertain times.

The Stanford Center for Population Health Sciences in partnership with Born in Bradford and the Centre for Applied Education Research cordially invite you to join a virtual conference where we will learn how researchers in the US and UK are tackling these issues.

Supporting Children in the Time of COVID-19 A School Based Approach to Health & Wellbeing @ Online Event
Aug 27 @ 8:00 am – 10:00 am
Supporting Children in the Time of COVID-19  A School Based Approach to Health & Wellbeing @ Online Event

Register here

In the wake of the COVID-19 pandemic, several support structures for children and their families have been disrupted. Underserved communities who were already disadvantaged prior to the pandemic now face further setbacks with regards to accessing digital resources, mental health services, food and housing support, and remote learning. On the frontlines of this battle are our educators who are grappling with the complexities of how to support their students during these uncertain times.

The Stanford Center for Population Health Sciences in partnership with Born in Bradford and the Centre for Applied Education Research cordially invite you to join a virtual conference where we will learn how researchers in the US and UK are tackling these issues.