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Samson Tu, MS,
Sr. Research Engineer,
Stanford Center for Biomedical Informatics Research,
Stanford University, &
Mor Peleg, PhD,
Visiting Associate Professor, Stanford University,
Dept. of Information Systems, University of Haifa
ABSTRACT:
Realizing the proven capabilities of computers in better processing of complex knowledge and data, medicine is heading toward computer-supported decision making. Following this vision, several research groups have developed languages that allow the representation of CPGs as computer-interpretable guidelines (CIGs). CIG engines match a patient’s data to the medical knowledge contained in the CIG in order to automatically deliver patient-specific recommendations at the point of care. However, existing CIG formalisms have not yet demonstrated in practice effective mechanisms for integrating CIGs to handle multi morbidities. The aim of this research is to develop and evaluate a new methodology for integrating the knowledge of CIGs for different chronic diseases to create non-conflicting management plans for patients with chronic comorbidities.
In the talk, I will present our methodology, which is a work in progress. Our methodology takes a goal-based approach that is modular and reusable. We envision a system of single-disease guidelines acting as agents whose invocation and conclusions are coordinated b a “Controller” agent that uses design patterns to recognize conflicts between different CPG goals and actions. The Controller then suggests ways in which these conflicts may be mitigated. It relies on CPG knowledge supplemented with general medical knowledge about the physiological effects of drugs and about drug hierarchies. Our approach is being implemented using existing commercial tools and standards. We use the PROforma CIG formalism and tools and the NDF-RT drug ontology for representing guideline and general medical knowledge, and the HL7 virtual medical record standard for structuring, storing, and retrieving patients’ data. The talk will focus on demonstrating how we have been developing our approach by applying information system analysis methods (Sequence Diagrams) to use-case patient scenarios of multi-morbidity patients.
The Nov. 12 symposium features research talks by young, leading scholars in global health policy research. Our keynote speaker is Christopher J.L. Murray, founder of the Global Burden of Disease project and the director of the Institute for Health Metrics and Evaluation. Topics include, among others, the effects of rising temperatures on child health in the developing world, environmental regulations in Mexico, and a hard look at the Millennium Villages Project.
Breakfast and lunch will be provided. A cocktail reception will be held in the Bechtel Conference Center from 6-6:45 pm following the keynote address by Chris Murray.
Instructor(s): Ashley Dunn, MPH & Michelle Bass, PhD, MSI
This class is designed to help research personnel (including research coordinators, post docs, administrative staff) learn about the NIH Public Access Policy. In addition, the class provides an opportunity for research personnel to hear about new features within the National Library of Medicine’s National Center for Biotechnology Information (NCBI) My Bibliography that can integrate with eRA Commons and help investigators, authors, and authorized delegates manage publications and compliance with the policy.
To register, please visit: http://lane.stanford.edu/classes-consult/laneclass.html?class-id=853.
Presenter: Marcella Alsan, MD, MPH, PhD
Associate Professor of Primary Care Outcomes Research, Stanford University
Marcella Alsan, MD, MPH, PhD, is an Associate Professor of Medicine at the Stanford School of Medicine and a Core Faculty Member at the Center for Health Policy / Primary Care and Outcomes Research.
Alsan’s research focuses on the relationship between health and socioeconomic disparities with a focus on infectious disease. Another vein of research focuses on the microfoundations of antibiotic overuse and resistance.
She received a BA degree in cognitive neuroscience from Harvard University, a master’s degree in international public health from Harvard School of Public Health, a medical degree from Loyola University, and a PhD in economics from Harvard University. She is board-certified in both internal medicine and infectious disease. She trained at Brigham and Women’s Hospital, completing the Hiatt Global Health Equity Residency Fellowship in internal medicine. She combined her PhD with an Infectious Disease Fellowship at Massachusetts General Hospital. She was an instructor of medicine at Harvard Medical School, prior to coming to Stanford. She currently is an infectious disease specialist at the Department of Veterans Affairs, Palo Alto.